Science Division Seminars
Today is January 19, 2020
Our next speaker will be Biochemistry Candidate RS from TBD speaking about
on January 28, 2020 in MAC 455 @ 11 AM.
Biochemistry Candidate MS, Candidate (email:TBD), TBD, "Characterization of the Structure, Dynamics, and Interactions of Proteins using NMR as an "Atomic Microscope"", January 14, 2020 in MAC 455 @ 11 AM. [area: biological]
Abstract - Focus on using NMR to characterize structure and function of peptides and proteins made both at OSU and at Denison University.
Joseph P. Straley, University of Kentucky, "Can Renewable Energy Replace Fossil Fuels?", January 16, 2020 in MAC 406 at 11AM. [area: physics]
Abstract - Burning fossil fuels is increasing the CO2 content of the atmosphere. This may lead to climate change. How hard will it be to convert to a renewable energy economy? I’ll discuss the issues that are involved.
- Biochemistry Candidate RS, Candidate, TBD, "TBD", January 28, 2020 in MAC 455 @ 11 AM. [area: biological]
- Biochemistry Candidate ED, Candidate (email:TBD), TBD, "TBD", January 30, 2020 in MAC 455 @ 11 AM. [area: biological]
- Geraldine Richmond, Professor of Chemistry, University of Oregon, "TBA - Roderick Seminar", March 27, 2020 in MAC 455. [area: physical]
Jay Baltisberger, Professor of Chemistry, Berea College and others, "New NMR Experiments on the JEOL ECZR 500", September 12, 2019 in MAC470 11AM. [area: physical]
Abstract - We have developed experiments for use in the CHM470 course as well as new research results using our newly installed 500 MHz NMR. The topics include 2D NMR identification of terpenes, diffusion ordered spectroscopy (DOSY), and solid state experiments on 31P, 29Si, and 17O containing materials.
- Andrea Kravats, Assistant Professor, Miami University of Ohio in Oxford OH, "Molecular chaperone interaction networks : Collaboration between Hsp90 and Hsp70 in protein activation", September 17, 2019 in 11 AM MAC 355. [area: biological]
Constance Bailey, Assistant Professor, University of Tennessee at Knoxville, "Chemical Transformations with Type I Polyketide Synthases: Investigations at the Domain, Module, and Host Levels ", October 17, 2019 in 11AM MAC455. [area: organic]
Abstract - Type I Polyketide Synthases (PKSs), pathways primarily found in soil bacteria (such as actinobacteria) present numerous opportunities to engineer a broad range of chemical scaffolds. Due to their modular nature, there is a great ability to predict the structure of the metabolite from sequence, termed the principle of collinearity. Harnessing this biological machinery can be implemented at three different levels. First, because there is exquisite stereochemical control arising from domains which intrinsically lack high binding affinity to their substrate (due to having their substrate delivered intramolecularly), there is a lot of potential to use these domains and engineer them as standalone biocatalysts for unnatural substrates. In our laboratory, we seek to determine how to perturb small energetic differences to effect stereoselectivity, with particular focus on the ketoreductase (KR) domain. At the next level, while engineering individual domains as biocatalysts has utility, understanding the interacting selectivities of the domains that comprise a module affords the ability to engineer a broad range of valuable chemical motifs. While the promise of the PKS platform has been extensively noted, implementing the power of PKSs has been hampered by lacking a full understanding of these interacting selectivities. We seek to transfer some of the findings from our individual domain engineering experiments to implement changes and engineer the multidomain systems. Finally, we seek to produce small molecules in various host organisms, which requires understanding how these proteins behave in various heterologous hosts, and the effects on folding, precursor availability, and protein activity.
- Jessie Dotson, NASA JPL, "TBA - Keplar/K2 Mission", October 18, 2019 in BURS Plenary - MAC 455 5PM. [area: astronomy]
Nancy Williams, Associate Professor of Chemistry, Claremont McKenna College, "The Hunt for the White Whale: A Decade-Long Pursuit of a Pyridonate Platinum Complex and a Chance to Repay the Gift", November 26, 2019 in 11 AM MAC 455. [area: inorganic]
Abstract - Nancy Williams received tenure in 2009, and has been making the most of it. She has spent the last decade working on two fundamental problems: finding a way to use the orbital properties of a ligand on platinum to promote the cleavage of the C-H bond in methane in the position trans to that ligand orbital, and coming to terms with the fact that she is trans, and how to make something good come of it. Nancy will tell the story of the synthesis of a compound she nicknamed, “the white whale”, a platinum complex that was ten years in the making. and the interesting chemistry it is displaying. She will explain how this played out over the backdrop of her transition, and share the lessons she has learned from working on two projects for a very long time, both of which seemed impossible when she began.
Dr. Samuel Awuah, Assistant Professor, University of Kentucky, "Gold Complexes in Medicine", January 24, 2019 in MAC 455 at 11 AM. [area: biological]
Abstract - Research into synthesis and characterization of gold complexes.
Lyle Roelofs, Berea College and others, "John Fenn Nobel Prize Dedication Symposium", March 30, 2019 in MAC Atrium. [area: physical]
Abstract - We will gather as the Nobel medal is displayed for the first official time in it's final display case in the new science building. We will have three seminars (including one from our college President) and some comments from the Fenn family
- Vicky Wysocki, The Ohio State University, "John Fenn Made Elephants Fly and Changed All Biomedical Research", March 30, 2019 in MAC Atrium 230PM. [area: biological]
- Amareth Lim, Eli Lilly & Company, "The Impact of Electrospray Ionization on the Characterization of Biopharmaceuticals", March 30, 2019 in MAC Atrium 200PM. [area: biological]
Geoff Coates, Professor of Chemistry, Cornell University, "In Pursuit of the Perfect Plastic", April 5, 2019 in Cargill Planetarium. [area: organic]
Abstract - Society depends on polymeric materials more now than at any other time in history. Although synthetic polymers are indispensable in a diverse array of applications, ranging from commodity packaging and structural materials to technologically complex biomedical and electronic devices, their synthesis and disposal pose important environmental challenges. The focus of our research is the development of sustainable routes to polymers that have reduced environmental impact. This lecture will focus on our research to transition from fossil fuels to renewable resources for polymer synthesis, as well as the development of polymeric materials designed to bring positive benefits to the environment.
Dr. Christine Nattrass, University of Tennessee, "Melting Nuclei", September 6, 2018 in CG 455 at 11:00 AM. [area: physics]
Abstract - Nuclei are melted in high energy collisions at the Large Hadron Collider at CERN, forming a phase of matter called the Quark Gluon Plasma. This phase of matter existed shortly after the Big Bang. As it expands and cools, it refreezes, forming particles called hadrons. We determine the properties of the Quark Gluon Plasma by studying these hadrons. I will discuss how we can figure out what the properties of this Quark Gluon Plasma are by studying these hadrons. I will also talk about what it is like to be a part of a large international experiment.
Dr. Jason Fry, Research Associate, UVA/ORNL, "Exploring the femto-scale to cosmology with cold neutrons", September 13, 2018 in CG 455 at 11 AM. [area: physics]
Abstract - Studying the nature of the neutron using different probes can reveal information about the universe from the smallest to largest scales. In this talk, I will go over fundamental symmetries of physics using neutrons, utilizing all four forces of nature: strong, weak, electromagnetism, and gravity. I will emphasize how much work has been done in the field and how much work we have left to enhance our understanding of the universe.
- Dr. Erendra Manandhar, Berea College, "TBA", September 27, 2018 in CG 455 at 11 AM. [area: organic]
Kristen Barnard, Berea College, "Do Stable Marriages Exist?", October 11, 2018 in MAC455 at 12-1PM.
Abstract - Graph Theory and Combinatorics
Elizabeth Cottrell, Geologist - Curator-in-Charge, Rock and Ore Collections, Smithsonian Institution, "Breathing the Earth", October 19, 2018 in Cargill Planetarium. [area: geology]
Abstract - When you hear the word “volcano,” what comes to your mind? Volcanoes are windows to Earth’s deep interior, revealing to us what lies beyond depths accessible to human exploration. Volcanoes shape the landscape, the hydrosphere, and human civilization. From natural disasters to climate change and from diamonds to Dr. Evil, we will explore volcano mysteries together.
Jacqulyn Noronha-Hostler, Assistant Professer, Rutgers University, "The Quest for Nature’s First and Most Perfect Liquid", October 19, 2018 in MAC 455 at 12PM. [area: physics]
Abstract - Milliseconds after the Big Bang the entire universe was filled with the most perfect liquid known to humanity- the Quark Gluon Plasma. The Quark Gluon Plasma has a number of peculiar properties, for instance, it flows like a liquid where friction effects are surprisingly small and it still maintains liquid-like properties on scales as small as the size of the nucleus of an atom. Because of the expansion and cooling of the Early Universe, the primordial Quark Gluon Plasma was extremely short lived and most of its signatures were washed away as the entire universe bloomed into existence. Over the past 15 years, collider experiments have been smashing heavy-ions together at 99.9999% the speed of light in order to produce a tiny droplet of the Quark Gluon Plasma with a radius of ~ trillionth cm. The collisions reach temperatures as high as a few trillion Kelvin which are able to "melt" ions into a dense "soup" of quarks and gluons that are constantly interacting with each other. In this seminar, the motion of this "quark gluon soup" is recreated using state-of-the-art numerical simulations that describe an almost perfect liquid moving at nearly the speed of light on high performance computers.
Faramarz Ismail-Beigi, Professor of Medicine and Biochemistry, Case Western Reserve University, "Insulin, Its Discovery, and Uses in Treatment of Diabetes", October 23, 2018 in MAC355 at 11 AM. [area: biological]
Abstract - Dr. Faramarz Ismail-Begi came to the United States from Tehran, Iran, in 1957 at the age of 15 to attend Oneida Institute in Oneida, KY, for his senior year of high school. He went on to attend Berea College, where he earned a degree in Chemistry in 1962. He completed his medical degree at Johns Hopkins School of Medicine, then completed postgraduate education and a PhD in Biophysics at the University of California San Francisco and Berkeley. In 1972, he returned to his native Iran to serve as Professor and Chairman of the Department of Medicine at Pahlavi University (now Shiraz University). He came back to the United States in 1984 and joined the Medicine and Biochemistry faculty at Columbia University. Since 1993, he has served as Chief of Endocrinology and Professor of Medicine, Biochemistry, and Physiology at Case Western Reserve University, University Hospitals of Cleveland, and the Cleveland VA Medical Center.
Larry Gratton, Berea College, "Complex Analysis", October 25, 2018 in MAC 455 at 12PM.
Abstract - Complex Analysis
Pat Heist, Research Chemist, Wilderness Trail Distillery, "Opportunities for Innovation in Fuel and Beverage Alcohol Production", October 30, 2018 in CG455 at 11AM. [area: biological]
Abstract - Fuel and beverage alcohol production has increased significantly in the U.S. in recent years. Here, we compare and contrast methods of fuel and beverage alcohol production and look at different strategies for increasing yield (gallons of alcohol produced per unit of feedstock). We will examine data generated throughout the production process and look at the microbiology and biochemistry of fermentation and how that factors into alcohol yield and flavor development. We will also look at ancillary areas of interest including prevention and control of microbial contaminants, assessing microbial communities in fermentation using molecular techniques, probiotics and other areas of innovation.
Shane Redmond, Eastern Kentucky University, "The Mathematics of Gerrymandering", November 8, 2018 in MAC 455 at 12PM.
Abstract - Geometry
Thomas Jarvis, Eastern Kentucky University, "The Death of Cute Ideas", November 15, 2018 in MAC455 at 11. [area: physics]
Abstract - With the development of increasingly complicated methods for studying fast events – like the motion of electrons in quantum dots or in proteins – using even faster laser pulses, it seemed for the last decade that maybe there was something far more exciting happening in plants and bacteria than we’d previously realized: maybe the strangely efficient transfer of solar energy to the centers of biochemical reactions depended on a quantum search algorithm, and maybe photosynthetic bacteria in mud at the bottom of the ocean and the oak trees outside the window had learned to harness quantum mechanics through evolutionary pressure. We’ll examine how you think you figure out something like this, how you actually figure out something like this, and what scientific rigor requires from us.
Suzanne Birner, Stanford University, "The Earth is Like a Box of Chocolates: Investigations into Our Planet’s Mysterious Filling", January 23, 2018 in SC106 at 11 AM. [area: geology]
Abstract - The Earth’s crust is divided into tectonic plates—large regions of oceanic and continental rock that shift relative to one another, pushing continents apart or bringing them together. When two plates move apart, new ocean floor is formed between them, as part of a volcanic process that produces a type of lava called basalt. At these plate boundaries, the solid residue of this magma production may also be exposed. These rocks, called peridotite, offer rare opportunities to study the material that makes up the Earth’s interior. In this talk, I will discuss the geochemistry of a suite of both peridotite and basalt rock samples dredged from the floor of the Southwestern Indian Ocean. In particular, I will demonstrate how the thermodynamic property of oxygen fugacity can provide insight into volcanic processes that initiate deep in the Earth’s upper mantle. I will show that, although the thermal history of peridotites must be carefully accounted for, both rock types ultimately give consistent information about the Earth’s interior. Finally, I will discuss both the implications of these results for important outstanding geologic questions, such as why the Earth has continents, as well as future research directions involving a range of geologic instrumentation.
Erkan Toraman, St. Lawrence University, "Constraining the Timing of Formation and Collapse of Mountains in North America", January 25, 2018 in SC106 at 11 AM. [area: geology]
Abstract - Convergent plate boundaries, where one tectonic plate dives under the other plate, such as modern Indian-Asian convergent boundary forming the Himalayas, are the locus of mountain building processes (orogenesis) on planet Earth. During the growth of an orogen, the outermost layer of Earth, continental crust, gets thicker owing to tectonic shortening and mantle-derived magma. Eventually, these systems reach a critical point where mountains cannot continue to grow vertically and horizontally and start to collapse under its own weight (orogenic collapse), which signifies the end of mountain building processes. During the collapse, mid-lower crustal rocks (>10 km) exhume rapidly to the surface along large fault zones. In this presentation, I will give examples from the North American Cordillera and the Adirondack Mountains, where we applied multiple dating techniques (geochronology) to provide better constraints on the formation and evolution of these mountains and to shed light on what mid-crustal rocks record during a planetary scale mountain-building events.
Alison Graettinger, University of Missouri, Kansas City, "When magma meets water: using experiments, fieldwork, and remote sensing to unravel explosive volcanic processes", January 30, 2018 in SC106 at 11 AM. [area: geology]
Abstract - One of the outstanding questions in volcanology is why the interaction between water and magma/lava sometimes leads to passive interactions, like the formation of pillow lava along the coast of Hawaii, and sometimes leads to violent explosions, and the production of dangerous ash and flying debris. Volcanic deposits produced by both processes provide information on the millimeter to decimeter scale interactions. Satellite imagery enables the remote observation of the deposits and landforms produced by eruptions on the hundreds to thousands of meters scale. Experiments provide an opportunity to evaluate the conditions that lead to these eruptions at the time scale of individual explosions. The incorporation of these three datasets is necessary to unravel these events and enable the evaluation of future hazards at volcanoes around the world.
Malcolm Forbes, Bowling Green State University, "Not So Free Radicals", February 1, 2018 in SC 106 at 11 AM. [area: organic]
Abstract - In this lecture I will give an overview of time-resolved and steady–state electron paramagnetic resonance (TREPR and SSEPR) spectroscopies describe and their application in the study of radical structure, dynamics, and reactivity. I will emphasize the use of these techniques in probing chemical systems experiencing restricted translational or rotational motion. Examples of such systems include polymer coatings, structured fluids, microbubbles, nanocrystals, reverse micelles, and vesicles. The TREPR technique is useful because it detects the primary photochemical events rather than rearrangements or secondary photolysis products. Examining radicals on the sub-microsecond time scale also allows us to examine the interplay between spin wave function evolution and diffusion in confined spaces (“spin chemistry”). In the second part of my talk I will demonstrate use of TREPR and SSEPR in polymer degradation chemistry, the topology of singlet oxygen production in heterogeneous structures such as vesicles and micelles, the photochemical “skunking” of beer by sunlight, biocompatible photopolymerization reactions, and the photoreactivity of sunless tanning lotions. Finally, I will present a brief history and overview of the Center for Pure & Applied Photosciences at BGSU, highlighting our faculty, recent research results, and our facilities.
Katie Salmeron, University of Kentucky, "INVESTIGATIONS OF INTERLEUKIN-1 ALPHA AS A NOVEL STROKE THERAPY IN EXPERIMENTAL ISCHEMIC STROKE", February 15, 2018 in SC106 at 11AM. [area: biological]
Abstract - Stroke is a leading cause of death and disability worldwide. Although rapid recognition and prompt treatment have dropped mortality rates, most stroke survivors are left with permanent disability. Approximately 87% of all strokes result from the occlusion of cerebrovasculature (ischemic strokes). Potential stroke therapeutics have included anti-inflammatory drugs, as well as many other targets with the goal of mitigating the acute and chronic inflammatory responses typically seen in an ischemic stroke. While these approaches have had great success in preclinical studies, their clinical translation has been less successful. Master inflammatory cytokines, such as IL-1, are of particular interest. IL-1's isoforms, IL-1 and IL-1 , were long thought to have similar function. While IL-1 has been extensively studied in stroke, the role of IL-1 during post stroke inflammation has been overlooked. Because IL-1 inhibitors have been unsuccessful in clinical application, we reasoned that IL-1 may provide previously unknown benefits to the brain after injury. We hypothesized that IL-1 could be protective or even accelerate reparative processes in the brain such as producing new blood vessels (angiogenesis) or neurons (neurogenesis). To test that IL-1 is protective after stroke, we tested IL-1 's protective effects on primary cortical neurons in in vitro models of stroke. We showed that IL-1 was directly protective on primary cortical neurons in a dose-dependent fashion. We then performed mouse middle cerebral artery occlusion stroke studies to determine the safety and of giving IL-1 in vivo. These studies showed that administering IL-1 acutely was neuroprotective. However, intravenous (IV) administration of IL-1 resulted in transient, hemodynamic changes following drug delivery. To minimize these systemic effects, we administered IL-1 intra-arterially (IA) directly into the stroke affected brain tissue, allowing us to significantly lower the concentration of administered IL-1 . In comparison to IV, IA IL-1 showed greater histological protection from ischemic injury as well as improved functional recovery following stroke, all without systemic side effects. To test that IL-1 could aid in neurorepair following stroke, we tested IL-1 's ability to help damaged blood vessels repair in vitro. We found that IL-1 significantly increased brain endothelial cell activation, proliferation, migration, and capillary formation. We tested IL-1 's proangiogenic properties in vivo by administering IL-1 three days following stroke. Delayed administration allowed us to separate IL-1 's acute neuroprotective effects from potential subacute angiogenic effects. We found that mice receiving IL-1 performed significantly better on behavioral tests and also showed greater vascularization within the penumbra two weeks following stroke. We also found that IL-1 treated animals showed more endothelial activation than vehicle treated animals. Finally, our studies showed that IL-1 treated animals showed increased early-phase neurogenesis with evidence of increased proliferation at the subventricular zone suggesting that IL-1 's beneficial effects are even more far-reaching than previously thought. In conclusion, our experiments suggest that the inflammatory cytokine IL-1 is neuroprotective and neuroreparative in experimental ischemic stroke and worthy of further study as a novel stroke therapy.
George M Whitesides, Professor of Chemistry, Harvard University, "Roderick Seminar 2018 - Soft Robotics", March 26, 2018 in SC106 at 4PM. [area: organic]
Abstract - "Robotics" is a field with broad interest: it combines mechanical engineering, information science, and animal physiology with manufacturing, workforce development, economics, and other areas. The most highly developed classes of robots have been build based on conceptual models provided by the body-plans of animals with skeletons (humans, horses), and have made it possible to carry out tasks that humans and animals could not (for a variety of reasons). We are interested in robots based a different, simpler class of organisms (invertebrates: starfish, worms, octopi). Because these organisms, and the robots having designs stimulated by them, have no skeletons, they provide enormous opportunities in materials and polymer science, rather than primarily in mechanical engineering. This seminar will outline one approach to soft robots, and suggest problems and opportunities in this new field.
George Whitesides, Harvard University, "Reengineering Chemistry", March 26, 2018 in SC106 at 12PM (CHM222). [area: organic]
Abstract - Chemistry is facing a set of very important challenges, and ones that are very different than those it has addressed in the past. This talk will outline some of the reason that the agenda of the field is changing, and how it may have to change in response.
Mary Robert Garrett, Associate Professor of Chemistry, Berea College, "The Synthesis of Tetracenes--A Possible Route to Renewable Energy", September 14, 2017 in SC106 at 11 AM. [area: organic]
Abstract - Work conducted at the University of Nottingham during Professor Garrett's one year sabbatical in 2016-2017
Johnathan N. Brantley, Assistant Professor of Chemistry, University of Tennessee at Knoxville, "Unmasking Latent Reactivity though Materials and Methods", September 19, 2017 in SC106 at 11AM. [area: organic]
Abstract - The interplay between macroscopic forces and chemical reactivity has attracted significant interest, given the potential to harness this surprising phenomenon for an array of applications in materials science and synthetic methodology. Polymer mechanochemistry, wherein exogenous forces drive chemistry within polymeric matrices, has emerged at the forefront of efforts directed toward harnessing stress to access new reactivity modes. Through the combination of experiment and theory, our efforts have unveiled fundamental insights that hold promise for multifarious applications. Salient examples include mechanical cycloreversions of 1,2,3-triazoles, as well as the suppression of certain dissociative reactions under strain. Moreover, concepts from these systems could be applied to rationally design biological molecules with predictable responses to force. Moving beyond a macromolecular focus, we have explored strategies for isolating reactive intermediates in trifluoromethylative processes and probing their innate chemistry. Taken together, this work suggests exciting directions for unlocking hidden reactivity to access new chemical space.
- Thomas Ferrell, University of Tennessee at Knoxville, "TBA", September 26, 2017 in SC106 at 11AM. [area: physics]
- Peter Kekenes-Huskey, Assistant Professor of Chemistry, University of Kentucky, "Understanding the chemistry of calcium signaling through computation: The Calcium, Calmodulin, Calcineurin signaling ‘triad’", October 12, 2017 in SC106 at 11 AM. [area: biological]
- Rocky Tuan, Professor and the Executive Vice Chairman for Orthopaedic Research, School of Medicine at the University of Pittsburgh, "Biomedical Research", October 20, 2017 in BURS at 5:30 PM in SC106. [area: biological]
- Bronson Messer, Senior Scientist in the Scientific Computing and Theoretical Physics Groups, Oak Ridge National Laboratory, "Simulating Stellar Death on Supercomputers: Phenomenology and Observables", November 2, 2017 in SC106 at 11AM. [area: physics]
Jiangjiang (Chris) Zhu, Assistant Professor of Chemistry, Miami University of Ohio, "Mass Spectrometry Based Metabolomics: Method Development and Application in Biomedical Research", November 7, 2017 in SC106 at 11 AM. [area: analytical]
Abstract - Metabolomics is the detection and identification of metabolites from any given biological system and is routinely applied as a tool for system biology research. Innovations in analytical technique and advances in bioinformatics ensured that now metabolomics can help us understand systems-level effects in many complex biological studies, including those focusing on cancer, inflammatory diseases, and gut microbiota studies. Among the available metabolomics techniques, mass spectrometry (MS)-based metabolomics offers an excellent combination of sensitivity and selectivity, and can be used for high-throughput metabolite analysis. This talk will focus on both the development and applications of novel mass spectrometry based metabolomics. We will introduce a couple of innovative MS-based methods that can be used for multiplex metabolites analysis, as well as give several successful examples of their applications in biomedical studies.
- Christine Nattrass, Assistant Professor of Physics, University of Tennessee at Knoxville, "Melting Nuclei", November 30, 2017 in SC106 at 11AM. [area: physics]
Ampofo Darko, Assistant Professor, University of Tennessee at Knoxville, "Principles of Strain in Synthesis and Catalysis", January 10, 2017 in SC101 at 11AM. [area: organic]
Abstract - The concept of strain, as discussed in terms of bond length, bond angle, and torsional distortions, has been an invaluable tool for organic chemists. Strain energies provide a way to examine compounds of unusual geometries and also offer an explanation of the driving force for certain reactions. The ability to harness the energy of strained compounds has resulted in very rapid reactions with numerous applications. Specifically discussed in this talk is ongoing work implementing the concept of strain in the design of ligands for rhodium complexes as catalysts in metal-carbenoid reactions.
David Cole, Professor of Geology, The Ohio State University, "Energy-Relevant Rock-Fluid Interactions: Where Geology, Chemistry and Physics Converge", January 31, 2017 in SC101 at 11AM. [area: geochemistry]
Abstract - Throughout Earth’s crust, fluids are the principal agents in transporting and localizing the Earth’s energy and mineral resources. Furthermore, the genesis and evolution of many different kinds of rocks are influenced by the flux of fluids which act as both reaction media and reactants. Among the many different types of crustal fluids, those containing volatile carbon, hydrogen and oxygen (C-H-O) species tend to dominate, and they commonly contain hydrocarbons such as methane as both a major constituent and an important energy source, particularly in sedimentary basins. Industry exploration and exploitation of shale gas (e.g. Marcellus, Utica, Barnett formations) have refocused attention on understanding the fundamental behavior of volatile hydrocarbon – brine – rock interactions. Interestingly, recent observations of hydrocarbons emanating from non-sedimentary systems (abiogenic), such as mid-ocean ridge hydrothermal systems or occurring within some crystalline rock-dominated Precambrian Shield environments have challenged the view that organic rich sediments provide the only significant source of crustal hydrocarbons. Hydrocarbons and associated aqueous solutions and other volatile species such as CO2 can occupy the pores or fractures of numerous types of complex heterogeneous earth materials present in the systems outlined above. This accessible porosity within rocks can span wide length scales (d as pore diameter or fracture aperture) including micro-, meso-, and macroporous regimes (d < 20 Å, 20 < d < 500 Å, and d > 500 Å, respectively, as defined by IUPAC). Porous solid matrices include rock or soil systems that contain clays and other phyllosilicates, zeolites, coal, graphite, or other carbonaceous-rich units; and weathered or altered silicates, oxides, and carbonates. A number of factors dictate how fluids, and with them reactants and products of intrapore transformations, migrate into and through these nano-environments, wet, and ultimately adsorb and react with the solid surfaces. These include the size, shape, distribution, and connectivity of these confined geometries, the chemistry of the solid, the chemistry of the fluids, and their physical properties. The dynamic behavior of fluids and gases contained within solids is controlled by processes occurring at the interface between the various phases (e.g., water-water, water-solute, water- volatile, water-solid, solute-solid, volatile-solid, etc.), as well as the rates of supply and removal of mobile constituents. The richness and complexity of rock-fluid interactions especially those involving nano-confined geometries only underscores the need to adopt a multidisciplinary approach when trying to quantify this behavior regardless of the C-H-O fluid type or the nature of the porous matrix. This presentation will touch upon some key examples of novel experimental and analytical techniques used in concert with state-of-the-art theory, modeling and simulation approaches to address these issues. In the Cole group at OSU there is a special emphasis on building synergistic links among results obtained from various advanced microscopy, neutron scattering and NMR studies which are integrated into our research portfolio with molecular dynamics modeling, to provide new phenomenological insights. The long-range goal of our research is to quantitatively link structure, dynamics and reactivity in complex mineral/C-H-O systems from the atomic to the molecular to the macroscopic levels, leading to predictive understanding of the consequences of fluid- rock interactions over the large time and length scales relevant to important geoscience ‘compartments’ such as deep sedimentary basins, tight shale, gas shale, continental and oceanic hydrothermal systems and formations targeted for CO2 storage.
Bob Howell, Professor of Chemistry, Central Michigan University, "Nontoxic Phosphorus Flame Retardants from Renewable Biosources", March 2, 2017 in SC 101 at 11 AM. [area: organic]
Abstract - Polymeric materials are pervasive in modern society and are largely responsible for the high standard of living enjoyed by citizens of much of the world. For most applications, polymeric materials must be flame retarded. Traditionally, organohalogen compounds, particularly brominated aromatics, have been prominent flame retardants. However, these materials are stable in the environment, tend to bioaccumulate, and may pose a risk to human health. Replacements are needed. Organophosphorus compounds offer the greatest potential to fill this need. They are readily available from synthesis and are generally less toxic than their organohalogen counterparts. In particular, effective organophosphorus compounds derived from renewable biosources offer the potential for low toxicity. In addition, they are independent of price fluctuations in the petrochemical markets. A variety of phosphorus compounds based on annually-renewable biosources (starch, plant oils, tartaric acid, chitosan) have been prepared and shown to provide good flame retardancy in DGEBA epoxy resin using standard small scale tests [limiting oxygen index (LOI), UL 94 vertical burn, microcalorimetry (mcc)].
Tammy Nicholson, Alltech, "Brewing and Distilling Applications", March 16, 2017 in SC101 at 11AM. [area: biological]
Abstract - I am focusing on the brewing and distilling process through fermentation and quality testing. The second half will discuss enzyme research I have done. So I was already thinking of addressing careers because I wanted to show the research side I do with product development and give a little starch chemistry. I thought this might be interesting and open up areas that they may have not thought about that relates to alcohol production in brewing, beverage distilling and fuel ethanol production.
Robert Crabtree, Professor of Chemistry, Yale University, "Roderick Seminar - Catalysts for Energy Applications", March 24, 2017 in SC106 at 4PM. [area: inorganic]
Abstract - Catalysis is an essential aspect of alternative energy research. Water splitting to O2 and H2 is needed for artificial photosynthesis, CH hydroxylation relates to functionalization of organic compounds and dehydrogenative oxidation extracts H2 from biomass products such as glycerol. An example of the latter is glycerol conversion to lactic acid, a much higher value product than the starting material
- Michael Kovash, Professor of Physics, University of Kentucky, "Quantum Weirdness - 11 AM in SC101", September 15, 2016 [area: physics]
- Paul Smithson, Associate Professor of Chemistry, Berea College, "Summer research - 11AM in SC101", September 27, 2016 [area: analytical]
- Julie Robinson, NASA, Johnson Space Center, Houston TX, "From Astronaut Bones to High Z particles: Significant Discoveries from the International Space Station - 3PM Convocation in Phelps Stokes", October 6, 2016 [area: astronomy]
Tom Troland, Professor of Physics, University of Kentucky, "The Milky Way and the Andromeda Galaxy - A Tale of Two Galaxies", November 3, 2016 in SC101 at 11AM. [area: astronomy]
Abstract - Where do new stars form in our Milky Way Galaxy? Where do they form in the neighboring Andromeda Galaxy? Observations of both galaxies at different electromagnetic wavelengths (radio, infrared, visible light and ultraviolet) yield the answer. Historically, astronomers relied upon studies of visible light. Today, they have access to the full range of electromagnetic radiation from the universe. Images of our Milky Way Galaxy and of the Andromeda Galaxy at different wavelengths reveal much about the structure of these galaxies and the locales within them where the next generation of stars is forming.
- Rick Page, Chair of Graduate Recruiting, Miami University of Ohio, "Dynamic Protein Quality Control by the CHIP/Hsp70 Complex", November 15, 2016 in SC101 at 11AM. [area: biological]
Susan Gardner, Professor of Physics, University of Kentucky, "Dark Matter & Energy - 11 AM in SC101", November 17, 2016 in SC101 at 11AM. [area: physics]
Abstract - The Standard Model of particle interactions, successful though it is, leaves many questions unanswered. Notably, it does not address the nature of dark matter, nor can it explain the observed cosmic surplus of matter over antimatter. The most popular models of "new physics" have been those that address these questions, by tying them to the theoretical origin of the weak interactions. However, with the Higgs discovery at the LHC and the non-observation of any other new effects, such enlargements of the Standard Model are becoming increasingly constrained. It is possible, rather, that essential clues as to its nature may first come from the appearance of light, weakly coupled new physics, which would not appear in LHC measurements, but to which low-energy, precision tests of the Standard Model are exquisitely sensitive. In this context, I will discuss an experimental anomaly in Be-8 nuclear transitions that may be interpreted as evidence for a new, weak force of some 12 fm in range. I will review the experimental evidence, its interpretation and implications, and emphasize what further experimental tests can be done to probe the experimental anomaly and its interpretation.
- Jason DeRouchey, Assistant Professor, University of Kentucky, "Understanding kinetics of protein corona formation on nanoparticles at 11AM in room 106 or 101", January 28, 2016 [area: biological]
- Erin Thorne & Jamie Hibbard, Southeastern Forensic Laboratory, London KY, "Forensic Science at 11AM in room 101", February 11, 2016 [area: forensic]
- Anes Kovacevic, Associate Professor, Berea College, "Exciting developments in Inorganic Chemistry", February 23, 2016 [area: inorganic]
- Karen Downey, Assistant Professor, SUNY Cortland, "Physical inorganic chemistry at 11AM", February 25, 2016 [area: inorganic]
Kelly Mouapi, Graduate Student, University of Louisville, "The Fantastic Four in Blood Coagulation: Fibrinogen and Factor XIII at 11 AM", March 24, 2016 [area: biological]
Abstract - Fibrinogen is the most abundant protein involved in blood coagulation and has been implicated in cardiovascular disease. During the formation of a blood clot, thrombin cleaves fibrinopeptides A and B from fibrinogen (AαBβγ)2 to form fibrin monomers (αβγ)2. Fibrin polymerization proceeds with the formation of protofibrils and a hard clot is only generated when the transglutaminase factor XIII (FXIII) introduces covalent γ- glutamyl-ε-lysyl bonds between specific reactive glutamines and lysines in the fibrin clot network. The αC region (Aα221-610) of fibrinogen contains numerous reactive glutamines in the flexible αC-connector (221-392) and a FXIII binding site within αC (371-425). MALDI-TOF mass spectrometry assays and 2D 15N-1H HSQC NMR studies have been carried out on fibrinogen αC (233-425), a segment containing three known reactive glutamines (Q237, Q328, and Q366). FXIIIa crosslinks these three glutamines to the lysine mimic glycine ethyl ester (GEE) in the order Q237 >> Q366 > Q328. To better characterize this system, single site mutants have been generated in which the reactive glutamines (Q) are individually replaced with inactive asparagines (N). Work with these mutants suggests that FXIIIa does not require crosslinking to occur in a sequential manner. Each glutamine can be cross-linked independently of the other. Due to its highly flexible nature, the fibrinogen αC region has not been observed by X-ray crystallography. 2D HSQC NMR studies on 15N-labeled αC (233-425) have now confirmed that this protein is intrinsically disordered. FXIIIa substrate specificity for specific reactive glutamines is predicted to be controlled by a combination of neighboring residues and the presence of regions of disorder. The knowledge gained from these studies can be used for subsequent assay and drug designs.
- Dr. Douglas Neckers, Founder of Spectra Group Limited, Spectra Group Limited, "3D Printing Chemistry", April 12, 2016 [area: analytical]
Neil Ayres, Associate Professor, University of Cincinnati, "Heparin inspired polymers for blood-contacting biomaterials at 11 AM in room 101", September 24, 2015 [area: organic]
Abstract - Biomaterials interface with biological systems to improve or treat these systems. The biocompatibility and performance of a biomaterial is dependent on the chemistry of the material. In our work we have focused on polymer blood-compatibility. Our primary goal has been to prepare synthetic polyureas that can mimic the function of heparin, a naturally occurring anticoagulant polysaccharide. This presentation will detail our progress in this area including the synthesis methodology we have developed, and our investigations into various structure property relationships. These relationships include the identity of pendant sugars on the polyurea and the isocyanates used to make the polymer. Recent work looking at shape memory properties will also be included. Neil Ayres received his Ph. D. in chemistry from the University of Warwick in 2003 where he worked for Prof. David Haddleton investigating surface initiated atom transfer radical polymerization (ATRP). After working as a post doc at the University of Southern Mississippi, the University of Akron, and the University of Utah, he became a professor in the department of chemistry at the University of Cincinnati in 2008. He received tenure and promotion to Associate Professor in 2014 and currently has research interests in synthetic chemistry of biomaterials and controlled polymerizations.
- Bogdan Dragnea, Provost Professor of Chemistry, Indiana University, "Chemical Physics with Virus-like Nanoparticles and Sunflower Seeds at 11 AM in room 101", September 29, 2015 [area: biological]
- Sharani Roy, Assistant Professor, University of Tennessee, "TBA", October 8, 2015 in 11 AM in SC101. [area: physical]
- Gregory Dale Smith, Indianapolis Museum of Art, "Conservation Science in Art at 11AM in room 101", October 22, 2015 [area: forensic]
- Roy Zent, Professor and Vice Chair of Research, Vanderbilt Univsity, "BURS Plenary talk at 5:30 PM in room 106", October 23, 2015 [area: biological]
- Bill Begley, Proctor and Gamble, ""Application of Mass Spectrometry in Industry: A quarter Century of Using Technology to Meet Business Needs" at 11 AM in SC101", February 12, 2015 [area: biological]
- Joshua Goldberger, Assistant Professor, The Ohio State University, ""Stimuli-Responsive Diagnostic and Therapeutic Self-assembling Peptide Vehicles" at 11AM in room 101", February 26, 2015 [area: biological]
- David Cunningham, Assistant Professor, Eastern Kentucky University, "Interface between Academics and Industry in room 106 at 11 AM", March 12, 2015 [area: forensic]
- Isabelle Lagadic, Northern Kentucky University, "Modified Clay Nanomaterials at 11 AM in SC106", April 7, 2015 [area: inorganic]
- Nick Marshall, Berea College, "Nature is Good at Sticky: Catechols for Surface Chemistry at 11 AM in room 106", September 9, 2014 [area: organic]
- John Anthony, Hubbard Professor of Chemistry, University of Kentucky, "Materials Chemistry: We care about properties, not molecules", September 30, 2014 [area: organic]
- Kathryn Uhrich, Professor of Chemistry, University of California, Riverside, "BURS Plenary Talk - PolyAspirin: Invention, Innovation, Inspiration and Inclusion", October 17, 2014 [area: organic]
- Tessa R Calhoun, Assistant Professor of Chemistry, University of Tennessee at Knoxville, "Advancing Optical Microscopy to Study the Interaction between Small Molecules and Cell Membranes at 11 AM in Room 101", October 30, 2014 [area: physical]
- Alvin Pasley, Sherwin Williams Company, "Process Chemistry at Sherwin Williams at 11AM in SC106", November 13, 2014 [area: physical]
- Dr. Tim Zwier, M. G. Mellon Distinguished Professor of Chemistry, Purdue University, "SC106 at 11AM", January 23, 2014 [area: physical]
- Dr. Margaret Ndinguri, Eastern Kentucky University, "Development of target specific drug delivery systems using bidentate and tridentate linkers - Inorganic Synthesis at 11AM in SC106", March 11, 2014 [area: inorganic]
- Dr. Matthew Nee, Western Kentucky University, "A Molecular Butterfly Effect: How Tiny Changes in Molecular Structure can have Global Impacts - Physical Chemistry at 11 AM in SC106", March 13, 2014 [area: physical]
- Clarissa E. Tatum, Eastman Chemical Company, "Life as an Industrial Chemist - SC106 at 11 AM", April 15, 2014 [area: analytical]
- Matthew Gentry, University of Kentucky IBS program, "From Human Neurodegenerative Disease to Biofuels at 11 AM in room 106", September 26, 2013 [area: biological]
- Paula K Shear, University of Cincinnati, "BURS Plenary Talk - "Neuropsychology of Epilepsy" at 5:15 room 106", October 18, 2013
- Thomas Troland, Professor of Physics, University of Kentucky, "Radio Astronomy and Star Formation - 11 AM in SC101", November 3, 2013 [area: astronomy]
- Matthew Saderholm, Berea College, "Peptide Research at Berea College", November 21, 2013 [area: biological]
- Shawn Campagna, University of Tennessee at Knoxville, "11 AM in room 106", December 3, 2013 [area: analytical]
- Nick Marshall, Berea College, "Making Molecular Wires on Surfaces", January 11, 2013 [area: organic]
- Michael Slade, Iowa State University, "Current Efforts Toward the Asymmetric Synthesis of a 'Privileged Substructure' in Organic Chemistry", January 18, 2013 [area: organic]
- David Watt, University of Kentucky IBS program, "11 AM room 106", February 21, 2013 [area: biological]
- Jay Baltisberger, Berea College, "A new experiment for echo train acquisition - PIETA at 11 in room 106", September 4, 2012 [area: physical]
- Rachel Allenbaugh, Murray State University, "Temperature Dependent Color Change for Use in Thermosensors", October 4, 2012 [area: analytical]
- Ziling Xue, University of Tennessee at Knoxville, "Analytical seminar at 11 in room 106", November 6, 2012 [area: analytical]
- Jane Jackman, The Ohio State University, "Biochemistry TBA at 11 in room 106", November 12, 2012 [area: biological]
- Craig Vander Kooi, Associate Professor of Chemistry, University of Kentucky IBS program, "Biochemistry research at 11 in room 106", January 26, 2012 [area: biological]
- Sanjeewa Goonesekera, University of Cincinnati, "Biomolecular engineering at 11 in room 106", January 27, 2012 [area: biological]
- Michael Best, Associate Professor of Chemistry, University of Tennessee at Knoxville, "TBA", February 7, 2012 in 11 AM in SC106. [area: organic]
- Darrin Smith, Eastern Kentucky University, "Analytical chemistry at 11 in room 106", March 20, 2012 [area: analytical]
- Mary Robert Garrett, Berea College, "Investigations Towards the Enantioselective Synthesis of beta-Ketoesters at 11 in room 106", April 12, 2012 [area: organic]
- Frank Yepez Castillo, Postdoctoral Scholar, Berea College, "Organic synthesis at 11 in room 106", September 6, 2011 [area: organic]
- Steve Meyers, Professor of Toxicology and Pharmacology, University of Louisville School of Medicine, "Toxicology and Pharmacology seminar at 11 in room 106", September 22, 2011 [area: biological]
- Dehua Pei, Professor of Chemistry, The Ohio State University, "Medicinal Chemistry at 11 in room 106", October 18, 2011 [area: biological]
- Rajesh Potineni and Scott Keller, Givaudan Flavors, "Chemistry of Food at 11 in room 106", November 17, 2011 [area: biological]
- Jon Camden, Professor of Chemistry, University of Notre Dame, "Plasmonic Nanostructures: From Sensing and Non-linear Optics to Energy Conversion at 11 in room 106", January 28, 2011 [area: analytical]
- Jennifer Ottesen, Associate Professor of Chemistry, The Ohio State University, "Biological chemistry at 11 in room 106", February 4, 2011 [area: biological]
- Oliver Thibault, University of Kentucky, "Calcium: An ion of life and death at 11 in room 106", February 15, 2011 [area: biological]
- Hairong Guan, University of Cincinnati, "Nickel and Iron Complexes as Efficient and Selective Catalysts for Carbon Dioxide Reduction and Organic Synthesis at 11 in room 106", February 22, 2011 [area: organic]
- Dr. Nathan Tice, Eastern Kentucky University, "TBA (SC 106), 3:00pm", September 17, 2010 [area: biological]
- Dr. Teresa Whei-Mei Fan, University of Louisville, "TBA (SC 106), 5:00pm", October 22, 2010 [area: biological]
- Dr. David Nicewicz, University of North Carolina, "TBA, (SC 106) 3:00pm", November 5, 2010 [area: organic]
- Dr. Kevin Revell, Murray State University, "TBA, (SC 106), noon", November 9, 2010 [area: organic]
- Dr. Dana Backman, NASA Ames Research Center, "SOFIA: NASA's New Airborne Observatory - 4PM SC106", January 8, 2010 [area: astronomy]
- David Tierney, Miami University of Ohio, "Integrated Paramagnetic Resonance of Biomimetic Co(II) at Noon in room 106", March 23, 2010 [area: inorganic]
- Tanea Reed, Eastern Kentucky University, "Biochemistry opportunities at EKU - 2PM room 106", April 8, 2010 [area: biological]
- Mary Robert Garrett, Berea College, "Enantioselective Synthesis of beta-Ketoesters via a Ketene-Claisen Condensation at 3:45 in room 210 Traylor (Art building by Phelps-Stokes)", April 9, 2010 [area: organic]
- Jessica Price Evans, Virginia Tech, "Highly Fluorinated Diels-Alder Polyphenylenes at 3PM in room 106", May 6, 2010 [area: organic]
- Dr. Frank Zamborini, University of Louisville, "Electrochemical and Optical Properties of Metal Nanostructures as a Function of Size and Chemical Environment, 3PM in SC106", October 15, 2009 [area: analytical]
- Dr. Kimberly Nixon, University of Kentucky, "plenary lecture for the Berea Undergraduate Research Symposium at 5 PM", October 23, 2009 [area: biological]
- Bob Compton, University of Tennessee, "The Earth's Vital Signs (SC106 4PM)", November 20, 2009 [area: physical]
- Erin Carlson, Indiana University, "Innovative Technologies for Natural Products Discovery at 3PM SC106", December 3, 2009 [area: organic]
- Marc R Knecht, Miami University of Ohio, "Bio-inspired Nanomaterials at 5 PM in SC 106", February 19, 2009 [area: biological]
- Craig A. Grapperhaus, University of Louisville, "Redox Regulated Binding of Ethylene to a Metal Thiolate at 5 PM in SC106", March 19, 2009 [area: inorganic]
- Gary E. Douberly, University of Georgia, "Liquid Helium Droplet Nanoreactors: Chemistry Near Absolute Zero at 3PM in SC106", April 9, 2009 [area: physical]
- Sam Li, National University of Singapore, "Nanoscale analytical techniques for environmental and biomedical applications @ 3PM in SC106", May 7, 2009 [area: analytical]
- Mark D. Watson, University of Kentucky, "Organic Electronic Materials Chemistry: Structure-property studies, synthesis, and devices in room 106 at 1 PM", October 2, 2008 [area: organic]
- Mark Lovell, University of Kentucky, "Plenary Talk for the Annual Berea Research Symposium at 5 PM in room 106", October 17, 2008 [area: analytical]
- Terry Gullion, West Virginia University, "Development and application of high-resolution solid-state NMR to biomolecules and polymers at 1 PM in SC 106", October 23, 2008 [area: physical]
- Michael Duncan, University of Georgia, "Spectroscopy and Photochemistry of Metal-Containing Clusters at 1 PM in SC 106", November 20, 2008 [area: physical]
- Aaron Amick, University of California, Irvine, "Methodology Development for Use in the Synthesis of Non-Natural and Natural Products" in SC106 at 4PM", December 2, 2008 [area: organic]
- Mary Robert Garrett, Centenary College, "Organic synthesis in room 106 at 3 PM", December 4, 2008 [area: organic]
- Jonathan Scheerer, Johns Hopkins University, "Organic synthesis in room 106 at 3PM", December 9, 2008 [area: organic]
- Christopher Kulp, Eastern Kentucky University, "Using Information Theory to Identify Relationships between Physical Systems @ 4 PM", March 7, 2008 [area: physical]
- Venkat Gopalan, The Ohio State University, "Biochemistry at OSU @ 2 PM", April 10, 2008 [area: biological]
- Hasan Palandoken, California Polytechnic State University at San Luis Obispo, "Organic Molecular Drug Targets for Brain Cancer Research", April 24, 2008 [area: organic]
- William Kennerly, Chemical Physics, "Computational Chemical Physics @ 4PM", April 25, 2008 [area: physical]
- Miranda Beam, University of Kentucky, "Pharmaceutical Sciences at UK", May 15, 2008 [area: organic]
- Dr. Jens Meiler, Vanderbilt University, "Redesign Proteins into Novel Antibiotics - 3 PM", September 20, 2007 [area: biological]
- Dr. Sheila David, University of California - Davis, "Dare to Repair: From Chemistry to Cancer - Time TBA, part of Berea College Undergraduate Research Symposium", October 19, 2007 [area: biological]
- Dr. Kenneth Kolb, Bradley University (ACS National Tour Speaker), "Glass, It's Many Facets - 5:30 PM", October 25, 2007
- Dr. Folami T. Ladipo, University of Kentucky, "The design of catalysts for ethylene trimerization and olefin polymerization - 1:30 PM", November 15, 2007 [area: organic]
- Christopher Aubin, Columbia University, "How the Origin of Life Can Come From a Computer", February 8, 2007 [area: physical]
- John Hopkinson, University of Toronto, "Magnetic Frustration @ 4PM SC106", February 15, 2007 [area: physical]
- D.W. Everson, Kentucky Crime Lab, "General Services of the Crime Lab and Toxicology Work, 1:30", February 22, 2007
- Martin Veillette, Berea College, "Bose-Einstein Condensate Research and Theory", February 26, 2007 [area: physical]
- Phillip S. Stevens, Indiana University, "Oh where oh where is OH? Measuring the elusive hydroxyl radical in the atmosphere @ 1:30 PM ", April 19, 2007
- Heather A. Rypkema, University of Louisville, "Kasha Violations in Fluorescent Molecules: evaluating relaxation pathways from higher excited states @ 1:30PM", May 3, 2007 [area: physical]
- David Smithrud, University of Cincinnati, "Host-Rotaxanes as Cellular Delivery Agents, 1:30 PM", September 21, 2006 [area: biological]
- Gang Cao, University of Kentucky, "4d and 5d Transition Metal Oxides: A New Frontier of Materials Research @ 4PM", September 29, 2006 [area: physical]
- Jurgen Rohr, University of Kentucky, "Combinatorial Biosynthesis and Studies on Biosynthetic Key Enzymes - Perspectives for Drug Discovery @ 1:30", October 19, 2006 [area: biological]
- Timothy P. Hanusa, Vanderbilt University, "The Allyl Group Grows Up: Chemical Consequences of a Sterically Enhanced Ligand @ 1:30 PM", November 16, 2006 [area: inorganic]
- Anes Kovacevic, Centre College, "Abnormal Carbene Ligands", January 18, 2006 [area: inorganic]
- Melissa Golden, University of North Carolina, Charlotte, "Fabrication of a Chemically Modified Electrode using a Chiral Ruthenium Bis(oxazoline) Complex", February 6, 2006 [area: inorganic]
- Douglas Mulford, Pepperdine University, "Fabrication of a Chemically Modified Electrode Using a Chiral Ruthenium Bis(oxazoline) Complex, 4PM Science 106", February 9, 2006 [area: inorganic]
- Stephen Testa, University of Kentucky, "Biochemistry Topic (3PM Science 106)", February 16, 2006 [area: biological]
- Jacquelynne Milingo, Franklin & Marshall College, "Planetary Nebulae: Swiss Army Knives of the Galaxy", February 23, 2006 [area: physical]
- Tracy Hodge, Salem State College, "Anatomy of a Starburst. Infrared Observations of the M33 HII Regions", February 27, 2006
- Matthew Fleenor, University of North Carolina, Chapel Hill, "The Landscape of Cosmological Structures: from Prism Light to Galaxy Superclusters", March 2, 2006
- Paul Deck, Virginia Institute of Technology, "Organometallic Ligand Research (3PM)", October 6, 2005 [area: inorganic]
- P. Andrew Evan, Queen's University, Kingston, Ontario CA, "New Organometallic Cross-Coupling Reactions for Target Directed Synthesis (3PM)", October 27, 2005 [area: inorganic]
- Dr. Gang Cao, University of Kentucky, "Novel Electronic Oxides: Living on the Edge", December 2, 2005 [area: physical]
- Jay Baltisberger, Berea College, "Improvements to the Solid State INADEQUATE Experiment at 2PM", December 8, 2005 [area: physical]
- M. Samy El-Shall, Virginia Commonwealth University, "Physical Chemistry of Clusters", March 4, 2005 [area: physical]
- Adam Smith (email:email@example.com), Air Force Research Lab, Wright-Patterson AFB OH, "Synthesis of Optoelectronic Materials for Organic Solar Cells (4pm in room 101)", April 4, 2005 [area: organic]
- Mark Cunningham (email:firstname.lastname@example.org), Atlanta Metropolitan College, "Anti-HIV Furamidine Prodrugs (2PM room 101)", April 7, 2005 [area: organic]
- John Thurston (email:email@example.com), University of Iowa, Iowa City, "From Molecules to Materials: Towards Single-Source Molecular Precursors For Advanced Oxides", April 11, 2005 [area: inorganic]
- Kelsey Cook, University of Tennessee, "Non-Covalent Interactions and Electrospray Mass Spectrometry: Alzheimer's Fibril Glue, and Caveats (5PM in conjunction with undergraduate research poster session)", October 29, 2004 [area: analytical]
- Kenneth A. Goldsby, Florida State University, "Inorganic Research and FSU", November 4, 2004 [area: inorganic]
- Philip Grandinetti, The Ohio State University, "Advances in Solid State NMR", November 16, 2004 [area: analytical]
- David Cliffel, Vanderbilt University, "Analytical and Electrochemistry", December 2, 2004 [area: analytical]
- Terry Collins (email:firstname.lastname@example.org), Carnegie Mellon University, "Green Chemistry (Science Seminar)", February 25, 2004
- Terry Collins (email:email@example.com), Carnegie Mellon University, "Green Chemistry", February 26, 2004
- David Igo (email:firstname.lastname@example.org), Chemical Development at GlaxoSmithKline, "Crystal-Form Screening of Drug Substances", March 18, 2004 [area: analytical]
- Darrin Smith, Eastern Kentucky University, "Surface Induced Dissociation: Surface Characterization and Peptide Sequencing (3PM)", April 8, 2004 [area: biological]
- John Fenn, Virginia Commonwealth University, "Electrospray Mass Spectrometry, general public lecture, 8PM Phelps-Stokes", September 30, 2003 [area: analytical]
- John Fenn, Virginia Commonwealth University, "Electrospray Mass Spectrometry for Scientists, 4 PM Science Building", October 1, 2003 [area: analytical]
- Harry Finklea, West Virginia University, "Kinetics of Proton Coupled Electron Transfer at Monolayer-coated Electrodes (Wednesday 5 PM)", October 15, 2003 [area: analytical]
- Mark Lipton, Purdue University, "Solid Phase Synthesis of Marine Natural Products, 5 PM Science Building", October 30, 2003 [area: organic]
- Anne-Frances Miller, University of Kentucky, "Biomolecular NMR Research at UK, 2 PM Science Building", November 14, 2003
- Stephen M. Holmes (email:email@example.com), University of Kentucky, "Inorganic coordination polymers", February 18, 2003 [area: inorganic]
- Debra Bautista (email:Debra.Bautista@EKU.EDU), Eastern Kentucky University, "Computational Organic Chemistry", March 4, 2003 [area: organic]
- Lori Watson (email:firstname.lastname@example.org), Indiana University, "What my hungry molecule ate for lunch: structure and reactivity of unsaturated Ru complexes", October 18, 2002 [area: inorganic]
- Bruce S. Ault (email:email@example.com), University of Cincinnati, "Oxidation Reactions of high valent transition metal compounds: the interplay of experiment and theory", October 30, 2002 [area: physical]
- Andre Sommer (email:SOMMERAJ@MUOhio.Edu), Miami University of Ohio, "Molecular Microspectroscopy for Industrial Forensics", November 13, 2002
- George R. Lester, Center for Catalysis and Surface Science and Northwestern University, "Gasoline/Electric Hybrid Vehicles: Interim or Long-term Technology Solution?", May 6, 2002 [area: physical]
- George R. Lester, Center for Catalysis and Surface Science and Northwestern University, "Does Atmospheric Carbon Dioxide Cause Greenhous e Warming? or Vice Versa?", May 7, 2002
- Ed Grant, Purdue University, "State Resolved Photoionization Dynamics of HCO and DCO ", September 26, 2001 [area: physical]
- David Wright, Vanderbilt University, "New Strategies for Fighting Malaria: Doing Good by Doing Well", October 10, 2001 [area: organic]
- Bill Heineman, University of Cincinnati, "New Concepts for Chemical Sensors", November 28, 2001 [area: analytical]
- Frank Shaw, Eastern Kentucky University, "Organo-metallic Cluster Compounds", March 1, 2001 [area: inorganic]
- Li Jing Sun, Harvard University, "DNA/Protein Binding Interactions", March 16, 2001 [area: biological]
- Richard Elder, University of Cincinnati, "Rhenium-Based Palliatives for the Treatment of Metastatic Canc er of the Bone", September 20, 2000 [area: inorganic]
- James M. Tanko, Virginia Polytechnic Institute and State University, "t-Butoxyl Radical as a Model for Hy drogen Abstraction in Biological Systems", October 18, 2000 [area: organic]
- Dr. Paul Bummer (email:firstname.lastname@example.org), University of Kentucky, "Introduction to Pharmaceutical Sciences", November 7, 2000 [area: biological]
- James P. Reilly, Indiana University, "MALDI Mass Spectrometery of Single Cells", November 15, 2000 [area: physical]
- Martin Gruebele, University of Illinois at Urbana-Champagne, "Femptosecond Laser Spectrosco py of Biomolecules", November 29, 2000 [area: physical]
- David A. Atwood, University of Kentucky, "Fundamental and Applied Aspects of Group 13 Chelate Complexes", March 10, 2000 [area: inorganic]
- Charles M. Lukehart, Vanderbilt University, "Preparation of Metal Alloy Nanocrystals for Single-Source Molecular Pre cursors: Catalysts for PEM or Direct Methanol Fuel Cells", November 9, 1999 [area: organic]
- Bernard A. Olsen, Lilly Research Laboratories, Lafayette, IN, "Chemical Process Developm enet", April 25, 1997 [area: organic]
- Phil Grandinetti, The Ohio State University, "Structure of Silicate Glasses with NMR", February 20, 1996 [area: analytical]
- Michael Wempe, University of Rochester Medical College, "New Approaches in Organic Chemistry", June 1, 1996 [area: organic]
- Pete Spielmann, University of Kentucky, "Biochemistry of DNA and NMR", October 19, 1995 [area: biological]
- Dave Wesley, Ashland Oil, "NIR Gasoline Analysis", January 19, 1995 [area: organic]
- Mark McMills, Ohio University, "Organic Synthesis", March 1, 1995 [area: organic]
- Celestia Pryor, University of the Pacific, "Bio-Organic Research", March 22, 1995 [area: organic]
- Roald Hoffman, Cornell University, "Chemical Beauty", October 13, 1994 [area: physical]
- Bill Heineman, University of Cincinnati, "Bioanalytical Chemistry", October 28, 1994 [area: analytical]
- Kelsey Cook, University of Tennessee, "Mass Spectrometry", December 1, 1994 [area: analytical]
- Joe Zwanziger, Indiana University, "Application of NMR to Borate Glasses", March 16, 1994 [area: physical]
- David Watt, University of Kentucky, "An Organic Chemists View of Geochemistry. How Organic Chemistry Can Contribute to Petroleum Exploration", March 30, 1994 [area: organic]
- Jim Lane, University of Wisconsin, Superior, "Catalytic Antibodies", May 5, 1994 [area: organic]
- Judith Shelling, Schmeiser, Olsen and Watts, "Protein Structure and Characterization", November 5, 1993 [area: biological]
- Dr. Brian McKeever, Merck & Company, "Carbonic Anhydrase and Rational Drug Design", October 23, 1992 [area: organic]
- Dr. David Gillum, Armco Research & Technology, Middletown OH, "Analytical Chemistry at ARMCO", December 1, 1992 [area: physical]
- Dr. M. Cecilia Yappert, University of Louisville, "Optical Spectroscopy Applied to Biological Studies", March 5, 1992 [area: physical]
- Dr. Dave Felten, University of Rochester, "Is there a Biological Basis for Mind-Body Interaction?", March 13, 1992 [area: biological]
- Dr. David Fraley, Georgetown College, "Chemistry of Soaps and Detergents: How to do Laundry and Wash Dishes", September 24, 1991 [area: analytical]
- Dr. Lee Roecker, Berea College, "Synthesis and Base Hydrolysis of Cobalt Sulfur Complexes", October 4, 1991 [area: inorganic]
- Professor Richard Elder, University of Cincinnati, "Curious Occurrences in the Metabolism of Gold-Based Antiarthritis Drugs", November 1, 1991 [area: biological]
- Professor Gideon Fraenkel, The Ohio State University, "Structure and Dynamic Behavior of Organolithium Compounds", November 8, 1991 [area: organic]
- Dr. Michael W. Vernon, University of Kentucky, "New Advances in Assisted Reproduction in Humans", November 26, 1991
- Dr. Dan McPherson, Oak Ridge National Laboratory, "Chemistry and Nuclear Medicine - Visiting Industrial Scientist Program", April 11, 1990 [area: physical]
- Dr. David Johnson, University of Kentucky while on sabbatical from Ferrum College, "Water Quality Monitoring and Research on Smith Mountain Lake", May 14, 1990 [area: analytical]
- Dr. Jim Holler, University of Kentucky, "A Microdroplet Mixing Technique for Studying Rapid Reactions", November 13, 1989 [area: analytical]
- Mark Lovell, graduate, "Research with LAMA and Graduate School Experiences", December 4, 1989 [area: biological]
- Dr. Jerry Sarquis, Miami University of Ohio, "Wonders of Chemistry - Chemical demonstrations", January 25, 1989 [area: analytical]
- Dr. Dennis Clouthier, University of Kentucky, "Hearing Aid Spectroscopy: Listening to the Screams of Molecules Tortured with Laser Beams", September 26, 1988 [area: physical]
- Dr. John R Grunwell, Miami University of Ohio, "Synthesis of Antitumor Antibiotics", November 14, 1988 [area: biological]
- Dr. Karen Eichstadt, Ohio University, "Exploring Summer Undergraduate Research Opportunities in Chemistry", December 5, 1988 [area: organic]
- Dr. Derek Davenport, Purdue University, "As the Sparks Fly Upward; 200 Years of Manned Flight", April 7, 1988 [area: physical]
- Dr. Matthew Stolte, Merrill-Dow, "Direction and Expectation After Berea", April 13, 1988
- Dr. John Meisenheimer, Eastern Kentucky University, "Tylenol - Its History and its toxic effects", October 21, 1987 [area: analytical]
- Dr. Rex Leuze, Oak Ridge National Laboratory, "Chemistry in the Nuclear Fuel Cycle", January 26, 1983
- William Dean, Hamilton County Coroner's Laboratory, "Chemists, Crooks and Killers: The Role of the Scientist in the Criminal Justice System", February 27, 1980 [area: analytical]
- Dr. Dorthy Gibson, University of Louisville, "Coal Conversion: A Source of Methane and Methanol", November 15, 1979 [area: organic]
Anyone interested in finding out more about these speakers or Berea College in general might contact Dr. Baltisberger via email at email@example.com