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2016 Berea College Research Symposium

The Berea Undergraduate Research Symposium (BURS), held this fall the weekend before the Berea College Trustees visit campus. This has been organized by the science programs in the past but participation is open to all members of the college community. In recent years we have structured the symposium with both talks and poster presentations as well as a plenary session.
The program for Fall 2016 will be held on Friday, October 7th. The 2016 BURS will start in the afternoon with student oral presentations, continue with student poster presentations, and end with a plenary talk by Dr. Karl Dawson, Vice President and Chief Scientific Officer at Alltech. His full biography is available in a pdf form. Karl Dawson has many responsibilities at Alltech, including handling the scientific research programs for the company. He also has an appointment at the University of Kentucky in the department of animal sciences. Some of his own personal research has focused on altering microbial activities and digestive processes in the gastrointestinal tract of animals for improved health and performance.

Using science to drive a global revolution in production agriculture:
Defining the tools for the future

Abstract - The challenge of building an agricultural system that will allow the world to sustainably support a population of more than 9 billion will require some staggering technological changes. Fortunately, our understanding of the basic biological mechanisms that control agricultural production are continuing to provide new tools that will allow for more efficient food production systems with less overall waste and environmental impact. However, the challenge will be to reconstruct our agricultural base and technical tool box in a way that the most beneficial technological advances can be rapidly adopted. This presentation will describe some recent scientific advances that promise to change the way we view agricultural production and describe the pathways and barriers to their implementation.
We will start at 2:30 PM with two simultaneous oral presentation sessions (15 minutes each) in rooms 101 and 106 of the Science Building. The sessions are grouped by theme as much as possible. The poster session starts at 3:30 and is held in the lobby of the science building with posters from various fields (previous posters from chemistry, biology, physics, psychology, sociology, education, African American Studies, economics, industrial arts, computer science, physical education & health, and mathematics). All students who pursued substantial research projects over the previous year are encouraged to present their research.
We have been hosting the BURS since 2001 and have records of participants going back to 2007 online (see links to the left).
Printable program for 2016 symposium
Students and faculty interested in attending or participating in the 2018 BURS should either contact Jay Baltisberger or Anes Kovacevic of the chemistry program. Alternatively a student may elect to register online via the link on the Chemistry department web server.

Impact of Polymer and Surfactant on Absorption of Poorly Water-Soluble Drug, Griseofulvin

Sean Gillette
Mentor: Patrick Marsac
Performed at University of Kentucky, College of Pharmacy
Griseofulvin is a commonly used antifungal drug on the market. The drug is used in the treatment of well-known infections like ringworm and athlete’s foot. Polysorbate and HPMC polymer are compounds that are used quite often in the drug industry to increase the solubility of drug in solution in the gastrointestinal tract. Those two compounds have been used as staple inactive ingredients in drug formulations in terms of increasing the bioavailability of drugs. But a current area of research on drug formulations, and the focus of this research, has been the impact that inactive ingredients (like Polysorbate/HPMC) have on the absorption of pure drug across the gastrointestinal membrane for uptake into the bloodstream. An experimental setup composed of two chambers separated from one another via a synthetic membrane was put together and used to test the effect of Polysorbate and HPMC polymer on Griseofulvin absorption across a synthetic membrane. HPMC polymer was found to have caused a linear increase in drug absorption across the synthetic membrane. Polysorbate was found to have caused a linear decrease in drug absorption across the synthetic membrane after a certain concentration of pure drug in solution was reached.

Registration for the 103rd Kentucky Academy of Sciences Meeting should follow this link KAS Registration

The following students have registered to do presentations for 2016

Oral Presentations

# Name Title Major
1 Emma, Reasoner Wildlife Response-Alaska Sealife Center biology
2 Jacquie Zimmerman The Expression of PD-L1 in the Hair Follicle abstract biology
3 Jillian Kendall and Robin Hauschner Examination of species richness and diversity of mosquitoes on the campus of Berea College abstract biology
4 Zachary Setters The role of TAp63 in epidermal wound healing abstract biology
5 Casey Tetidrick, Aubrey Melton, Chioma Amaechi, Willie Gosnell, Gladys Kamau, Yunpeng Xia A Peer-Assisted Learning (PAL) Model that Increases Student Success in Anatomy and Physiology biology
6 Sean Nilan Seed Germination Ecology of the Endangered Yellow Gentian (Gentiana flavida): A Population in Peril? abstract biology
7 Aaron Morgan Seed Dormancy in Calycanthus floridus (Carolina allspice): Does Time of Dispersal Affect Dormancy Break and Germination? abstract biology
8 Sunaina Sherchan Clinical and Research Experience at Bill Wilkerson Center for Speech Pathology and Audiology biology
9 Seth Reasoner Characterization of a novel delivery system of cyclic dinucleotides for efficient innate immune activation abstract chemistry
10 Kyaw Hpone Myint Encapsulation of Nanoparticles during Polymer Micelle Formation: A Dissipative Particle Dynamics Study abstract chemistry
11 Tatiana Mikhailova Developing selective inhibitors of USP7 deubiquitinating enzyme abstract chemistry
12 Albert, Artiles Counting Trees mathematics

Poster Presentations

# Name Title Major
1 Haylie Prottsman, Kaitlynn Rothwell Nutritional Management and Reproductive Performance of Replacement Heifers Raised in Sustainable Production Systems at Berea College and Community Producer Operations agriculture and natural resource
2 Nina Meneses, Olivia Slater, Favour Akabogu, Robin Hauschner, Aubrey Melton, Casey Tetidrick, Jillian Kendall Climate Change and the Effect of Temperature on the Release of Proterometra macrostoma (Trematoda: Digenea) Cercariae from their Snail Intermediate Host, Pleurocera semicarinata (Gastropoda: Pleuroceridae) abstract biology
3 Favour Akabogu, Robin Hauschner, Nina Meneses, Olivia Slater, Kaitlyn Reasoner, Hsuan Peng, Lin Peng, Chi Peng Seasonal Changes in Maturation of Adult Cotylaspis insignis (Trematoda: Aspidogastridae) Recovered from the Fat Mucket, Lampsilis radiata luteola (Bivalvia: Unionidae) abstract biology
4 Meghan Kramer Development of therapeutics for sleep apnea targeting Kir2.4 potassium channels abstract biology
5 Amber Follin, Ambra Pozzi Expression of DDR-2 Flag in Human Embryonic Kidney Cells abstract biology
6 Hanna Abe Analysis of neuromasts in pkd2 mutant zebrafish biology
7 James Bryson McCarthey The application of Glyoxalase one crispr cas-9 knockout cells for the study of neuropathy. abstract biology
8 Hsuan Peng Intraepithelial cells in an NOD IL10-/- ABo DQ8 mouse model of celiac disease abstract biology
9 Aubrey Melton Determining the effectiveness of a PAL (Peer-Assisted Learning) program in Anatomy and Physiology II biology
10 Marah Zeidan Improving Long-Term Outcomes in Retinoblastoma Survivors abstract biology
11 Wesley Saintilnord, Rafael Mendoza The stability of environmental temperatures influences thermal plasticity in the Eastern newt (Notophthalmus viridescens). abstract biology
12 Rebekah Ponder Visualizing spatiotemporal gene expression of the Sonic Hedgehog (Shh) gene during axoltl limb development and regeneration abstract biology
13 Tyller Culver, Jeremy Wilde Isolation and Characterization of Antibiotic Resistant Staphylococcus in the Berea College Community- a pilot study abstract biology
14 Monica Moran Effect of Ziram and methylmercury on ubiquitin activating enzyme E1 and microtubules in human neurons and mouse neuro2A cells abstract biology
15 Monica Powell & Hope Thoms Isolation and Characterization of Plasmid DNA from Non-Pathogenic Commensal Escherichia coli biology
16 Brenna MacMillan & Million Beshah Design and Synthesis of Novel Neurotensin Analogs abstract chemistry
17 Job Limo Investigating the Role of Magnesium Stearate in Tablet Formulations abstract chemistry
18 Selena Ledesma Alonso Synthesis and Characterization of the ZorO Protein abstract chemistry
19 Christinia Patel Functional role of the cytoplasmic tail of α subunit of α3β1 integrin in migration and adhesion to LM-511 abstract chemistry
20 Boubacar Cherif The Bioluminescent Detection of HIV Persistency abstract chemistry
21 Samuel A. Effoe Teratogen Toxicity in Organotypic Culture Models abstract chemistry
22 Jonah Rector Activity of Small Molecule Endoplasmic Reticulum Proteostasis Regulators abstract chemistry
24 Tomas Flores & Chris James Laboratory Study of Glyphosate Degradation in Berea Forest Soils chemistry
25 Carlos Andres Berejnoi Bejarano & Chann Makara Han Degradation of Glyphosate in Berea College Forest Soils chemistry
26 Aubree Zimmer Probing actinomycin Y5 biosynthesis by investigating Z-family homologs abstract chemistry
27 Priscila Elizabeth Garcia Garcia & Savannah Osborne Land Use History, Soil Characterization and Invasive Species in the Berea College Forest chemistry
28 Helina Asrat Managing pests in stored wheat: Do organic methods work? chemistry
29 Sean Gillette Impact of Polymer and Surfactant on Absorption of Poorly Water-Soluble Drug, Griseofulvin abstract chemistry
30 Michael James & Kateryna Nabukhotna Engineering Novel Substrates for the Neuropeptidase Neurolysin abstract chemistry
31 Bhavesh Ramkorun Comparing two unrooted phylogenetic X-trees mathematics
32 Malachi Holden Adjoints and Hierarchies mathematics
33 Susan Bonta & Constantine Botimer Spreading Knowledge of the Berea College Art Collection to the Larger Community abstract other
34 Rashad Hayden & Bethany Turner Diversity and Community Policing other
35 Eddie Henderson & Charity Ryan A Metaphorical Staircase abstract other
36 Ashley Aiken & Victoria Slaughter Implementation of Digital Fabrication Technologies in Ceramic Practice abstract other
37 Talha Rehman The CLAS12 Forward Tagger Detector at Jefferson Lab abstract physics
38 Dustin Watts Fabrication of MEMS Microrobots abstract physics
39 Nathanael Bodine Developing High Entropy Alloys and the Impact of Annealing on the Crystalline Structures abstract physics
40 Mackenzie Ridley Optimizing a Processing Parameter of Direct Metal Laser Deposition for Porosity Reduction of Thin Film TiB2+AlMgB14 on High Carbon Steel Tracks abstract physics
41 Tanner Thompson Thermo-Magnetic Properties of High Entropy Alloys abstract physics
42 Robert Barnes Thermo-Magnetic Properties of High-Entropy Alloys abstract physics
43 Abdul Ali Eissar (2+1)-dimensional Causal Dynamical Triangulations abstract physics
44 Denzell Barnett & Guillermo Ramos-Macias Development of Open Source Computer Simulation for STEM fields abstract physics
45 Kyree Hobson & Simeon Huff Evaluation of the Berea Summer Food Service Program sociology