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Office Hours:
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Contact:
jay_baltisberger@berea.edu

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2016 Berea College Research Symposium

The Berea Undergraduate Research Symposium (BURS), held this fall the weekend before the Berea College Trustees visit campus. This has been organized by the science programs in the past but participation is open to all members of the college community. In recent years we have structured the symposium with both talks and poster presentations as well as a plenary session.
The program for Fall 2016 will be held on Friday, October 7th. The 2016 BURS will start in the afternoon with student oral presentations, continue with student poster presentations, and end with a plenary talk by Dr. Karl Dawson, Vice President and Chief Scientific Officer at Alltech. His full biography is available in a pdf form. Karl Dawson has many responsibilities at Alltech, including handling the scientific research programs for the company. He also has an appointment at the University of Kentucky in the department of animal sciences. Some of his own personal research has focused on altering microbial activities and digestive processes in the gastrointestinal tract of animals for improved health and performance.

Using science to drive a global revolution in production agriculture:
Defining the tools for the future

Abstract - The challenge of building an agricultural system that will allow the world to sustainably support a population of more than 9 billion will require some staggering technological changes. Fortunately, our understanding of the basic biological mechanisms that control agricultural production are continuing to provide new tools that will allow for more efficient food production systems with less overall waste and environmental impact. However, the challenge will be to reconstruct our agricultural base and technical tool box in a way that the most beneficial technological advances can be rapidly adopted. This presentation will describe some recent scientific advances that promise to change the way we view agricultural production and describe the pathways and barriers to their implementation.
We will start at 2:30 PM with two simultaneous oral presentation sessions (15 minutes each) in rooms 101 and 106 of the Science Building. The sessions are grouped by theme as much as possible. The poster session starts at 3:30 and is held in the lobby of the science building with posters from various fields (previous posters from chemistry, biology, physics, psychology, sociology, education, African American Studies, economics, industrial arts, computer science, physical education & health, and mathematics). All students who pursued substantial research projects over the previous year are encouraged to present their research.
We have been hosting the BURS since 2001 and have records of participants going back to 2007 online (see links to the left).
Printable program for 2016 symposium
Students and faculty interested in attending or participating in the 2018 BURS should either contact Jay Baltisberger or Anes Kovacevic of the chemistry program. Alternatively a student may elect to register online via the link on the Chemistry department web server.

Design and Synthesis of Novel Neurotensin Analogs

Brenna MacMillan & Million Beshah
Mentor: Matthew Saderholm
Performed at Berea College
This undergraduate research team focused on solid phase peptide synthesis (SPPS). This method of synthesis is a relatively fast and efficient technique, in which each individual amino acid is coupled on to the carboxylic terminal of the next amino acids, forming the specific sequence necessary to create the chosen peptide. Specifically, this group synthesized variations of the fluorogenic peptide Neurotensin, which primarily contributes to dopamine regulation in the human body, but also plays a role in the nervous system. There are thirteen amino acids in the peptide Neurotensin, and by altering the tenth or eleventh amino acid in the sequence, one can observe the various functional and reactional changes that might occur. The amino acid sequence for Neurotensin is Glu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH. The research team chose to replace either positions ten or eleven with larger, more polar amino acids or smaller amino acids with higher hydrophobicity. The team chose these specific locations on the peptide for the altercations because this is where Neurolysin naturally bisects the peptide between the amino acids Proline and Tyrosine, during regulation of the amount of Neurotensin in the body. These peptides were purified and analyzed by several different instruments including the HPLC, MALDI-TOF, Mass spectrometer, and fluorometer assays.


Registration for the 103rd Kentucky Academy of Sciences Meeting should follow this link KAS Registration

The following students have registered to do presentations for 2016

Oral Presentations

# Name Host Title Mentor Major
1 Emma, Reasoner Alaska Sealife Center Wildlife Response-Alaska Sealife Center Dr. Ronald Rosen biology
2 Jacquie Zimmerman University of Denver Anchutz Medical Campus The Expression of PD-L1 in the Hair Follicle abstract Dr. Dennis Roop biology
3 Jillian Kendall and Robin Hauschner Berea College Examination of species richness and diversity of mosquitoes on the campus of Berea College abstract Sarah Blank biology
4 Zachary Setters University of Colorado Anschutz Medical Campus The role of TAp63 in epidermal wound healing abstract Dr. Dennis Roop biology
5 Casey Tetidrick, Aubrey Melton, Chioma Amaechi, Willie Gosnell, Gladys Kamau, Yunpeng Xia Berea College A Peer-Assisted Learning (PAL) Model that Increases Student Success in Anatomy and Physiology Sarah Blank biology
6 Sean Nilan Berea College Seed Germination Ecology of the Endangered Yellow Gentian (Gentiana flavida): A Population in Peril? abstract Christopher A. Adams biology
7 Aaron Morgan Berea College Seed Dormancy in Calycanthus floridus (Carolina allspice): Does Time of Dispersal Affect Dormancy Break and Germination? abstract Christopher A. Adams biology
8 Sunaina Sherchan Vanderbilt University Medical Center Clinical and Research Experience at Bill Wilkerson Center for Speech Pathology and Audiology Dr. Ann Marie Tharpe biology
9 Seth Reasoner Vanderbilt University Medical Center Characterization of a novel delivery system of cyclic dinucleotides for efficient innate immune activation abstract Manny Ascano, PhD chemistry
10 Kyaw Hpone Myint The Ohio State University Encapsulation of Nanoparticles during Polymer Micelle Formation: A Dissipative Particle Dynamics Study abstract Dr. Barbara Wyslouzil & Dr. Lisa Hall chemistry
11 Tatiana Mikhailova Harvard Medical School Developing selective inhibitors of USP7 deubiquitinating enzyme abstract Ilaria Lamberto, Xiaoxi Liu, Sara Buhrlage chemistry
12 Albert, Artiles Berea College Counting Trees Dr. Beth Kelly, Dr. James Blackburn-Lynch mathematics

Poster Presentations

# Name Host Title Mentor Major
1 Haylie Prottsman, Kaitlynn Rothwell Berea College Nutritional Management and Reproductive Performance of Replacement Heifers Raised in Sustainable Production Systems at Berea College and Community Producer Operations Quinn Baptiste agriculture and natural resource
2 Nina Meneses, Olivia Slater, Favour Akabogu, Robin Hauschner, Aubrey Melton, Casey Tetidrick, Jillian Kendall Berea College Climate Change and the Effect of Temperature on the Release of Proterometra macrostoma (Trematoda: Digenea) Cercariae from their Snail Intermediate Host, Pleurocera semicarinata (Gastropoda: Pleuroceridae) abstract Ron Rosen & Sarah Blank biology
3 Favour Akabogu, Robin Hauschner, Nina Meneses, Olivia Slater, Kaitlyn Reasoner, Hsuan Peng, Lin Peng, Chi Peng Berea College Seasonal Changes in Maturation of Adult Cotylaspis insignis (Trematoda: Aspidogastridae) Recovered from the Fat Mucket, Lampsilis radiata luteola (Bivalvia: Unionidae) abstract Ron Rosen biology
4 Meghan Kramer Vanderbilt University Medical Center Development of therapeutics for sleep apnea targeting Kir2.4 potassium channels abstract Dr. Jerod S. Denton biology
5 Amber Follin, Ambra Pozzi Vanderbilt University Medical Center, Nashville, TN Expression of DDR-2 Flag in Human Embryonic Kidney Cells abstract Corina Borza biology
6 Hanna Abe Mayo Clinic Analysis of neuromasts in pkd2 mutant zebrafish Caroline Sussman, PhD biology
7 James Bryson McCarthey Vanderbilt university The application of Glyoxalase one crispr cas-9 knockout cells for the study of neuropathy. abstract Jim Galligan biology
8 Hsuan Peng Mayo Clinic Intraepithelial cells in an NOD IL10-/- ABo DQ8 mouse model of celiac disease abstract Dr. Eric Marietta and Dr. Joseph Murray biology
9 Aubrey Melton Berea College Determining the effectiveness of a PAL (Peer-Assisted Learning) program in Anatomy and Physiology II Sarah Blank biology
10 Marah Zeidan Vanderbilt University Improving Long-Term Outcomes in Retinoblastoma Survivors abstract Dr. Debra Friedman biology
11 Wesley Saintilnord, Rafael Mendoza Berea College The stability of environmental temperatures influences thermal plasticity in the Eastern newt (Notophthalmus viridescens). abstract Patrick Mineo biology
12 Rebekah Ponder University of Kentucky Visualizing spatiotemporal gene expression of the Sonic Hedgehog (Shh) gene during axoltl limb development and regeneration abstract Dr. Ashley Seifert biology
13 Tyller Culver, Jeremy Wilde Berea College Isolation and Characterization of Antibiotic Resistant Staphylococcus in the Berea College Community- a pilot study abstract Dr. Dawn J. Anderson biology
14 Monica Moran Vanderbilt University Effect of Ziram and methylmercury on ubiquitin activating enzyme E1 and microtubules in human neurons and mouse neuro2A cells abstract Dr. Diana Neely biology
15 Monica Powell & Hope Thoms Berea College Isolation and Characterization of Plasmid DNA from Non-Pathogenic Commensal Escherichia coli Dawn Anderson biology
16 Brenna MacMillan & Million Beshah Berea College Design and Synthesis of Novel Neurotensin Analogs abstract Matthew Saderholm chemistry
17 Job Limo University of Kentucky, College of Pharmacy Investigating the Role of Magnesium Stearate in Tablet Formulations abstract Dr. Eric Munson chemistry
18 Selena Ledesma Alonso University of Tennessee, Knoxville Synthesis and Characterization of the ZorO Protein abstract Shawn Campagna chemistry
19 Christinia Patel Vanderbilt University Medical Center Functional role of the cytoplasmic tail of α subunit of α3β1 integrin in migration and adhesion to LM-511 abstract Olga Viquez, PhD chemistry
20 Boubacar Cherif University of Miami The Bioluminescent Detection of HIV Persistency abstract Emre Dikici chemistry
21 Samuel A. Effoe University of Pittsburgh Teratogen Toxicity in Organotypic Culture Models abstract Peter Alexander & Rocky Tuon chemistry
22 Jonah Rector The Scripps Research Institute Activity of Small Molecule Endoplasmic Reticulum Proteostasis Regulators abstract R. Luke Wiseman chemistry
23 Marco Santos Vanderbilt University IMPACT OF SRCR DOMAINS IN THE FUNCTIONALITY & LOCALIZATION OF LYSYL OXIDASE LIKE 2 IN DIABETIC NEPHROPATHY. abstract Dr. Alberto Lopez-Jimenez chemistry
24 Tomas Flores & Chris James Berea College Laboratory Study of Glyphosate Degradation in Berea Forest Soils Paul Smithson chemistry
25 Carlos Andres Berejnoi Bejarano & Chann Makara Han Berea College Degradation of Glyphosate in Berea College Forest Soils Dr. Paul C. Smithson chemistry
26 Aubree Zimmer University of Kentucky College of Pharmacy Probing actinomycin Y5 biosynthesis by investigating Z-family homologs abstract Dr. Steven Van Lanen chemistry
27 Priscila Elizabeth Garcia Garcia & Savannah Osborne Berea College Land Use History, Soil Characterization and Invasive Species in the Berea College Forest Dr. Paul C. Smithson chemistry
28 Helina Asrat Berea College Managing pests in stored wheat: Do organic methods work? Sean Clark chemistry
29 Sean Gillette University of Kentucky, College of Pharmacy Impact of Polymer and Surfactant on Absorption of Poorly Water-Soluble Drug, Griseofulvin abstract Patrick Marsac chemistry
30 Michael James & Kateryna Nabukhotna Berea College Engineering Novel Substrates for the Neuropeptidase Neurolysin abstract Matthew Saderholm chemistry
31 Bhavesh Ramkorun Berea College Comparing two unrooted phylogenetic X-trees James Blackburn-Lynch and Beth Kelly mathematics
32 Malachi Holden Berea College Adjoints and Hierarchies James Blackburn-Lynch and Beth Kelly mathematics
33 Susan Bonta & Constantine Botimer Berea College Art Collection Spreading Knowledge of the Berea College Art Collection to the Larger Community abstract Meghan Doherty other
34 Rashad Hayden & Bethany Turner Berea College Diversity and Community Policing Kennaria Brown other
35 Eddie Henderson & Charity Ryan Berea College A Metaphorical Staircase abstract Daniel Feinberg other
36 Ashley Aiken & Victoria Slaughter Berea College Implementation of Digital Fabrication Technologies in Ceramic Practice abstract Raymond Gonzalez other
37 Talha Rehman Jefferson Lab The CLAS12 Forward Tagger Detector at Jefferson Lab abstract Troy Messina/Dr. Marco Battaglieri physics
38 Dustin Watts University of Louisville Fabrication of MEMS Microrobots abstract Dr. Dan Popa physics
39 Nathanael Bodine Berea College Developing High Entropy Alloys and the Impact of Annealing on the Crystalline Structures abstract Troy Messina physics
40 Mackenzie Ridley South Dakota School of Mines and Technology Optimizing a Processing Parameter of Direct Metal Laser Deposition for Porosity Reduction of Thin Film TiB2+AlMgB14 on High Carbon Steel Tracks abstract Dr. William Cross physics
41 Tanner Thompson Berea College Thermo-Magnetic Properties of High Entropy Alloys abstract Troy Messina physics
42 Robert Barnes Berea College Thermo-Magnetic Properties of High-Entropy Alloys abstract Troy Messina physics
43 Abdul Ali Eissar Bard College (2+1)-dimensional Causal Dynamical Triangulations abstract Joshua Cooperman physics
44 Denzell Barnett & Guillermo Ramos-Macias Berea College Development of Open Source Computer Simulation for STEM fields abstract Martin Veillette physics
45 Kyree Hobson & Simeon Huff Berea College, Grow Appalachia, and the Berea Summer Food Service Program Evaluation of the Berea Summer Food Service Program Andrea Woodward sociology