Dr. Miranda (Gibson) Beam
Visiting Assistant Professor of Organic Chemistry
Visiting Assistant Professor of Organic Chemistry
B.S. Chemistry, Berea College, 2003
Ph.D. Pharmaceutical Sciences, University of Kentucky, 2008
miranda_beam@berea.edu
Ph.D. Pharmaceutical Sciences, University of Kentucky, 2008
miranda_beam@berea.edu
Society Memberships
- American Chemical Society
- Rho Chi Honor Society
- Amercian Association for the Advancement of Science
- American Association of Pharmaceutical Scientists
Academic and Professional Honors
- 2006 30th National Medicinal Chemistry Symposium Travel Award
- 2005-06 Peter G Glavinos, Jr. Ph.D. Fall Graduate Student Travel Award
Presentations
- CERMACS, Cincinnati OH, 2007, oral presentation "Varying he substrate specificity of the Baeyer-Villiger type monooxygenase mtmOIV using site directed mutagenesis to produce superiour analogs of the anticancer agent Mithramycin"
- National Medicinal Chemistry Symposium, Seattle WA, 2006, poster presentation "Altering substrate specificity of the Baeyer-Villiger type monooxygenase MtmOIV by site directed mutagenesis"
Publications
- Gibson M, Nur-e-alam M, Lipata F, Oliveira MA, Rohr J, "Characterization of Kinetics and Products of the Baeyer-Villiger Oxygenase MtmOIV, the Key Enzyme of the Biosyntheic Pathway Towards the Natural Product Anticancer Drug Mithramycin from Streptomyces argilaceus", Journal of the American Chemical Society 127(50); 17594-17595, 2005.
- Beam M, Noinaj N, Wehenkel M, Rohr J, "Crystal Structure of MtmOIV, a Baeyer-Villiger Monooxygenase from the biosynthetic pathway of the anticancer agent Mithramycin", J Biochem in prep.